A New Horizan on Relationship of Genetical Findings and HIV Infection
HIV is a global problem and still poses a great threat to the public health. Because there is no prophylactic vaccine or efficacious therapeutic method, the best way for controlling HIV is to detect susceptible populations.
HLA gene polymorphisms have defined role in infection and progression of HIV. In the other hand, gene chips have the great capability of simultaneous assessment of several genes in a short period of time. Based on this, HIV-gene Chip, is being designed to assay several HLA gene polymorphisms in relation to HIV in a large number of high risk populations. HIV-gene Chip is a probe on which those genes are immobilized. Genes of the populations under assessment hybridise to them as the target. There are no limitations in the number of genes arrayed and people who are assayed. The results of data analysis will be definitely so helpful for local healthcare officials and finally the outcomes will be in hands of WHO to organize its future programs in management of HIV-AIDS infection.